Known as a tiny collection of atoms which form relatively stable sub-microscopic aggregates, clusters are ideal systems for observing quantum effect and studying the initial state in forming macroscopic matter; and are associated with many chemical reactions and material-changing processes, such as catalysis, combustion, crystal nucleation & growth, etc. We work on metal clusters through gas-phase chemistry to bridge atoms and condensed-phase materials, including cluster reactivity and superatom exploration for genetic materials.